opentrons magnetic module

The opentrons magnetic module, derived from the well-known American life sciences group Opentrons Labworks, is a highly respected laboratory automation module. Its broad application fields cover multiple industries such as molecular biological diagnosis, biotechnology, medical care, food testing, forensic identification, gene sequencing, and protein engineering, fully demonstrating its versatility and importance.

1. Working principle of opentrons magnetic module 1. Magnetic bead binding stage (1) Magnetic bead selection: First, select appropriate magnetic beads. The surface of these magnetic beads is usually modified with ligands that specifically bind to target molecules (such as antibodies, oligos. nucleotides, etc.). (2) Sample processing: Mix the biological samples to be processed (such as blood, tissue homogenate, cell lysate, etc.) with magnetic beads, and allow the target molecules to interact with the magnetic beads under appropriate conditions (such as temperature, pH value, time, etc.) Ligand binding on the bead surface. 2. Magnetic field separation stage (1) Magnetic field effect: When the mixed solution is placed in the magnetic field of the opentrons magnetic module, the magnetic beads are attracted to the vicinity of the magnet in the module due to magnetic effect, thereby separating from other components in the solution. (2) Washing and rinsing: Under the action of a magnetic field, the magnetic beads bound to the target molecules can be washed and rinsed to remove unbound impurities and excess reagents. 3. Target molecule release stage (1) Condition change: By changing conditions (such as pH value, temperature, adding specific reagents, etc.), the target molecule is dissociated from the ligands on the surface of the magnetic beads and released into the solution. (2) Collection and analysis: The released target molecules can be collected and subjected to subsequent analysis and detection, such as PCR amplification, sequencing, mass spectrometry analysis, etc. 4. Automated control (1) Program setting: opentrons magnetic modules are usually used in conjunction with automated control systems. Users can set corresponding programs according to experimental needs, including magnetic bead selection, sample processing, magnetic field action time, washing times, and condition changes. Parameters etc. (2) Automated operation: Under program control, the opentrons magnetic module can automatically complete the above-mentioned operations at each stage without manual intervention, greatly improving experimental efficiency and accuracy. 5. Compatibility and flexibility (1) Reagent compatibility: opentrons magnetic module is compatible with most reagents and magnetic beads on the market, providing users with more choices. (2) Sample processing: Up to 96 samples can be processed simultaneously at a time to meet the needs of high-throughput experiments.

2. Technical parameters and application scenarios of opentrons magnetic module 1. Temperature control module: temperature range 4~95℃, temperature accuracy ±1℃at65℃, temperature uniformity ±1℃at65℃. 2. Thermal cycle module: The temperature range of the module base is 499°C, the temperature range of the module upper cover is 37110°C, the maximum heating rate of the base is 4.25°C/s between room temperature and 95°C, and the maximum cooling rate of the base is 2.0°C between 95°C and room temperature. /s. 3. Magnetic bead purification module: It uses high-strength lift-type N52 neodymium magnets and is compatible with a variety of laboratory equipment and magnetic bead products. opentrons magnetic modules are widely used in experimental scenarios that require magnetic bead extraction, such as DNA/RNA extraction, protein purification, cell separation, etc. It plays an important role in biological sciences, medical research, drug development and other fields.

3. Company background of opentrons magnetic modules opentrons Labworks is an American life sciences group, which includes four major business divisions: Robotic Robotics, PRL Diagnostic Laboratory, NEO Cell Engineering and AI Artificial Intelligence. Hechuang Bioengineering (Shenzhen) Co., Ltd. is a wholly-owned subsidiary of opentrons Group established in July 2017. It is affiliated to the Robotics Division and integrates the research and development, production and sales of laboratory automation instruments and consumables. opentrons' products enjoy a high reputation worldwide and are widely used in major scientific research institutions and laboratories.

As a laboratory automation module carefully developed by Opentrons Labworks, the opentrons magnetic module not only greatly improves experimental efficiency and data quality with its high efficiency, accuracy, and flexibility, but also provides scientific researchers with a reliable and convenient experimental tool. Help them continue to move forward on the road of exploring the mysteries of life.