Magnetic bead nucleic acid extraction instrument

The magnetic bead nucleic acid extractor is an automated equipment that utilizes the specific recognition and efficient binding of nucleic acids by magnetic beads to achieve separation effects by adsorbing nucleic acids through magnetic beads to extract nucleic acids (DNA or RNA). Now let us understand the magnetic bead nucleic acid extraction instrument from the working principle, product features, technical parameters, etc.:

1. Working principle

The magnetic bead nucleic acid extraction instrument realizes automated extraction of nucleic acids through the specific adsorption of nucleic acids by magnetic beads and combined with automated operating devices such as robotic arms or magnetic rods. The specific process includes: sample lysis, nucleic acid adsorption to the magnetic bead surface, washing to remove impurities, and elution to obtain pure nucleic acid. In each step, the magnetic beads are precisely manipulated under the influence of a magnetic field to achieve efficient extraction of nucleic acids.

2. Product features

1. High degree of automation: The magnetic bead nucleic acid extraction instrument can automatically complete the sample loading, lysis, adsorption, washing, elution and other steps, greatly reducing manual operations and improving work efficiency.

2. High-throughput: Some models of machines can process multiple samples at one time, such as 96 or more, to meet the needs of large-volume sample processing.

3. High purity and high yield: Through the specific adsorption and efficient washing of magnetic beads, high-purity nucleic acids can be extracted with a high yield.

4. No pollution: The entire extraction process is carried out in a closed system, avoiding the risk of cross-contamination.

5. Simple operation: The instrument is usually equipped with a graphical operation interface, and users only need to follow the prompts to operate without complicated training.

6. Wide scope of application: suitable for extracting nucleic acids from various samples such as whole blood, plasma, serum, tissues, cells, etc.

3. Technical parameters

The technical parameters of magnetic bead nucleic acid extraction instruments vary depending on the brand and model, but generally include the following:

1. Number of channels: the number of samples that can be processed at one time, such as 96, 32, etc.

2. Sample volume: The sample volume range that can be processed, such as 30-1000μl.

3. Magnetic bead recovery rate: usually greater than 99%, indicating the adsorption efficiency of magnetic beads to nucleic acids.

4. Difference between purification wells: indicates the difference in purity of nucleic acids extracted between different well positions, and generally requires a small amount.

5. Nucleic acid extraction time: The time required to complete an extraction is generally between a few minutes and tens of minutes.

6. Heating temperature range: The heating temperature range that the instrument can control is used for steps such as sample lysis.

7. Temperature control accuracy: The accuracy of temperature control affects the extraction effect.

8. Shaking and mixing mode: The shaking mode used to mix samples and reagents can be adjusted as needed.

9. Operating noise: The noise level when the instrument is running is generally required to be low.

10. Built-in UV germicidal lamp: Some models of machines have built-in UV germicidal lamp for disinfection and prevention of contamination.

4. Suggestions on purchasing

When purchasing a magnetic bead nucleic acid extraction instrument, it is recommended to consider the following factors:

1. Laboratory needs: Choose the appropriate model and throughput according to the sample processing volume and type of the laboratory.

2. Brand and quality: Choose well-known brands and high-quality products to ensure the stability and reliability of the instrument.

3. After-sales service: Understand the supplier’s after-sales service policy, including repairs, maintenance, training, etc.

4. Cost-effectiveness: Comprehensively consider the price of the instrument, cost of consumables, operating costs and other factors, and select products with high cost-effectiveness.

Through the brief introduction above, we have a preliminary understanding of the magnetic bead nucleic acid extraction instrument. It is a highly flexible, scalable, and high-throughput nucleic acid extraction equipment, and has demonstrated its inexhaustibility in the field of modern molecular biology. Comparable efficiency, automation, and superior nucleic acid extraction purity. We believe that the unlimited development potential of the magnetic bead nucleic acid extraction instrument will enable it to play a more important role in future scientific research.