Flex应用专题 | 解锁蛋白质谱前处理自动化的无限潜能
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Liquid preparation is a vital part of the production process, and its accuracy and efficiency are directly related to the quality and stability of the final product. In this link, liquid dispensers play an indispensable role. With their professional skills and rigorous attitude, they carefully prepare solutions that meet standards from various raw materials according to established formulas and process requirements.
1. Liquid dispensing tools 1. Liquid dispensing tank (1) Definition and purpose: The liquid dispensing tank, also known as the preparation tank or the mixing tank, is a mixing container for mixing one or several materials according to process proportions. It is widely used in dairy, chemical, food, beverage, pharmaceutical and other industries. (2) Features: reasonable design, advanced technology, in line with national GMP certification requirements. The tank mostly adopts a vertical double-layer structure. The inner tank is polished with high precision. The inner cylinder is wrapped with a spiral belt for heating and filled with polyurethane material for insulation. The parts that come into contact with the liquid are made of 316L material, and the rest are made of 304 material to ensure the hygiene and safety of the product. Equipped with a stirring system, temperature control system, etc. to ensure the uniformity and stability of the liquid preparation process. 2. Agitator (1) Definition and purpose: The agitator is a key component in the liquid preparation tank and is used to fully mix various raw materials evenly. (2) Features: There are various stirring forms, including magnetic stirring, stirring blade stirring, etc., which can be selected according to specific needs. The stirring speed is adjustable to adapt to the mixing requirements of different materials. The material is excellent, resistant to corrosion and high temperature, ensuring stability and reliability for long-term use. 3. Measuring instruments (1) Definition and purpose: Measuring instruments include balances, measuring cylinders, pipettes, etc., which are used to accurately weigh or measure raw materials. (2) Features: High precision, able to ensure accurate input of raw materials. Easy to use, simple and quick to operate. The materials are mostly corrosion-resistant materials such as glass or stainless steel, which are easy to clean and disinfect. 4. Transfer pump (1) Definition and purpose: The transfer pump is used to transfer the prepared liquid from the liquid preparation tank to the next process or storage container. (2) Features: The flow rate is stable and can ensure the continuous transportation of liquid. The material is excellent, resistant to corrosion and wear, and extends its service life. Different types of delivery pumps can be selected according to actual needs, such as peristaltic pumps, centrifugal pumps, etc. 5. Other auxiliary tools (1) Cleaning tools: such as CIP cleaning balls, etc., used for cleaning and disinfection of liquid distribution tanks and pipelines. (2) Detection instruments: such as thermometers, liquid level gauges, etc., used to monitor parameters such as temperature and liquid level during the liquid preparation process. (3) Protective equipment: such as protective glasses, gloves, etc., used to protect the safety of operators.
2. Solution preparation work content 1. Preparation of reagents and solutions (1) Preparation work: According to experimental or production needs and in accordance with established formulas and operating procedures, accurately weigh and measure the required raw materials to prepare solutions. This includes but is not limited to operations such as dissolving, diluting, and mixing chemical reagents, biological reagents, pharmaceutical ingredients, etc. (2) Recording and labeling: During the preparation process, it is necessary to record in detail the operating steps of each step, the batch number of the raw materials used, preparation time, preparation volume and other information, and clearly mark the prepared solution with relevant information, such as name, concentration , expiration date, etc. to ensure the traceability and safety of use of the solution. 2. Storage and use management (1) Storage management: Responsible for storing the prepared solution according to specified conditions, such as temperature, humidity, light, etc., to ensure the stability and effectiveness of the solution. At the same time, stored solutions need to be checked regularly to detect and deal with abnormalities in a timely manner. (2) Requisition management: Responsible for the requisition and registration of solutions according to the needs of experiments or production, ensuring the rational use of solutions and avoiding waste. During the application process, it is necessary to check the recipient's identity, usage amount and other information, and keep relevant records for future reference. 3. Equipment operation and maintenance (1) Equipment operation: Be familiar with and master the operating procedures and precautions of various equipment in the liquid preparation workstation, such as high-precision pipettes, automated liquid handling systems, mixers, temperature control systems, etc. During the operation, it is necessary to strictly follow the procedures to ensure the normal operation of the equipment and the accuracy of the experimental results. (2) Equipment maintenance: Regularly maintain and maintain the equipment in the liquid preparation workstation, including cleaning, calibration, replacement of wearing parts, etc. Through maintenance work, the service life of the equipment can be extended, the operating efficiency of the equipment can be improved, and the failure rate can be reduced.
The liquid preparation work involves many aspects such as the preparation, storage and collection management of reagents and solutions, equipment operation and maintenance, and other related work. Liquid dispensers need to have solid professional knowledge, a rigorous work attitude and a high sense of responsibility to ensure the smooth progress of the work and the accuracy of the experimental results.
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